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Medchemexpress LLC CPI-455 | 1628208-23-0 | 99.0% | 278.31 g/mol | C16H14N4O | 50 MG
Supplier: Medchemexpress LLC HY10042150MG
CPI-455 is a small-molecule pan-KDM5 (histone demethylase) inhibitor with an IC50 of approximately 10 nM for KDM5A. It elevates global H3K4me3 levels and reduces drug-tolerant persister cancer cells in cell-based models. The compound is supplied as a white to off-white solid for research use, with storage and analytical documentation provided by the supplier.
- Potent KDM5 inhibition (IC50 ≈ 10 nM).
- Elevates global H3K4 trimethylation (H3K4me3).
- Demonstrated activity in cell-based models reducing drug-tolerant persister cells.
- Supplied as a white to off-white solid for in vitro research use only.
- Analytical purity reported near 99%; confirm lot certificate for exact value.
- Includes structural identifiers (SMILES) and supporting documentation for characterization.
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