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Medchemexpress LLC CPI-637 | 1884712-47-3 | MFCD30489741 | 99.9% | 386.45 g/mol | C22H22N6O | 10 MG
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Supplier:  Medchemexpress LLC HY10048210MG

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CPI-637 is a selective, cell-active CBP/EP300 bromodomain inhibitor used in epigenetic and cancer biology research. It demonstrates low-nanomolar biochemical potency against CBP and EP300 and shows cellular activity in the submicromolar range.

  • Selective inhibition of CBP and EP300 bromodomains (IC50 = 0.03 μM and 0.051 μM).
  • Reduced activity against BRD4 BD1 (IC50 = 11.0 μM).
  • Cellular activity with CBP BRET EC50 ≈ 0.3 μM.
  • High reported purity (~99.9%) suitable for research applications.
  • Chemical formula C22H22N6O; molecular weight 386.45 g·mol⁻¹.

Catalog No. 50-002-14983


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