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Cayman Chemical cPLA2 asy Buffer 1ea
Supplier: Cayman Chemical 7650301 EA
An SHP-2 inhibitor (IC50 E76K (IC50 0.17 UM) reduces the levels of phosphorylated ERK in a reporter assay using KYSE-520 cancer cells (IC90 0.012 UM) and inhibits proliferation of the same cells (IC50 0.32 UM) reduces tumor volume in KYSE-520 and NCI H358 mouse xenograft models at 30 or 100 mg/kg two times per day
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