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AdipoGen Crf2 mAb MS112-IIA1
Supplier: AdipoGen AG27B6318C050
Recombinant Antibody. Recognizes Crf2 from Aspergillus fumigatus. Possible cross-reactivity with Crf1, Crf2 and Asp f9 Reference 2. Applications ELISA, FUNC, IHC, WB, IF. Clone MS112-IIA1. Isotype Human IgG1. Formulation Liquid. In PBS. Aspergillus fumigatus is a common airborne fungal pathogen for humans. It frequently causes an invasive aspergillosis IA in immunocompromised patients with poor prognosis. Potent antifungal drugs are very expensive and cause serious adverse effects. Their correct application requires an early and specific diagnosis of IA. Encoded by CRF1 gene, the Crf protein family contains three protein variants Crf2 protein, amino acids 333 aa long, Asp f9 protein 292 aa, first identified as an allergen using serum from Aspergillus-allergic patients and Crf1 395 aa, also named Crh5. The glycosyol hydrolase/glycosidase Crf2 catalyzes the hydrolysis of glycosidic bonds in complex sugars and is located in the cell wall of the growing hyphae.
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