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HORIZON DISCOVERY BIOSCIENCES LIMITED CRISPRa Lentiviral dCas9-VPR Reagents, hEF1a, Viral Particles - 50µL, 10^7 TU/mL
Supplier: HORIZON DISCOVERY BIOSCIENCES LIMITED VCAS11922
The CRISPR activation (CRISPRa) system is a variation of the canonical CRISPR-Cas9 used for creation of double-strand breaks in genomic DNA. It utilizes a nuclease-deactivated S. pyogenes Cas9 (dCas9), often called "dead Cas9", that is fused to one or more transcriptional activators. When paired with a well-designed guide RNA that targets a gene near a promoter region, the gene's native transcription start site is activated.
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