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AdipoGen CRP h mAb rec TOB5-D4
Supplier: AdipoGen AG27B6321C050
Recombinant Antibody. Recognizes human C-reactive protein CRP. Applications ELISA, WB. Clone TOB5-D4. Isotype Human IgG1. Formulation Liquid. In PBS. C-reactive protein CRP is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components chromatin, histones, etc., plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages.
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