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Medchemexpress LLC CSF1R-IN-1 | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g/mol | C25H20F3N5O2 | 100 MG
SDP

Catalog No. 5000246412
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CSF1R-IN-1 is a potent small-molecule inhibitor of the colony stimulating factor 1 receptor (CSF1R) with subnanomolar enzymatic potency (IC50 = 0.5 nM). It has demonstrated good intestinal permeability and favorable oral pharmacokinetics in mice, supporting its use in preclinical in vivo pharmacology studies related to tumor-associated macrophage biology, cancer, and inflammation research.

  • Potent CSF1R inhibition (IC50 = 0.5 nM).
  • Suitable for preclinical in vivo pharmacology studies.
  • Demonstrates good intestinal permeability in Caco-2 assays.
  • Favorable oral pharmacokinetic profile in mice.
  • Available in solid and DMSO solution formats for dosing flexibility.
  • High reported purity for research use.

Catalog No. 50-002-46412 Supplier Medchemexpress LLC Supplier No. HY101774100MG
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CSF1R-IN-1 is a potent small-molecule inhibitor of the colony stimulating factor 1 receptor (CSF1R) with subnanomolar enzymatic potency (IC50 = 0.5 nM). It has demonstrated good intestinal permeability and favorable oral pharmacokinetics in mice, supporting its use in preclinical in vivo pharmacology studies related to tumor-associated macrophage biology, cancer, and inflammation research.

  • Potent CSF1R inhibition (IC50 = 0.5 nM).
  • Suitable for preclinical in vivo pharmacology studies.
  • Demonstrates good intestinal permeability in Caco-2 assays.
  • Favorable oral pharmacokinetic profile in mice.
  • Available in solid and DMSO solution formats for dosing flexibility.
  • High reported purity for research use.

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