Invitrogen™ Human CSNK1A1L, GST Tag Recombinant Protein

Catalog No.	Quantity
A33354	1 mg
A30494	10 μg
A32865	100 μg

Catalog No. A33354 Supplier Invitrogen™ Supplier No. A33354

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This CSNK1A1L recombinant human protein (full length) was expressed in insect cells. CSNK1A1L recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Full Length, Recombinant, Active The gene accession number for CSNK1A1L is AAH28723.1.

CSNK1A1L serine/threonine kinase or CK1-alpha dynamically associates with the CBM complex upon T cell receptor engagement to participate in cytokine production and lymphocyte proliferation which has a contrasting role by subsequently promoting the phosphorylation and inactivation of CARMA1. It governs antigen-receptor-induced NF-kappa-B activation and human lymphoma cell survival. These kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins including CTNNB1, PER1, and PER2. CSNK1A1 also participates in Wnt signaling.It may play a role in segregating chromosomes during mitosis, as well as, cytoskeleton diassembly which may regulate epithelial cell migration.

Specifications

• Accession Number: Q8N752
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 0.1mM EDTA, 25% glycerol, 10mM glutathione, 0.1mM PMSF, 0.25mM DTT, 150mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 122011
• Molecular Weight (g/mol): 65.4 kDa
• Name: Human CSNK1A1L, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: casein kinase 1 alpha 1 like; casein kinase 1, alpha 1-like; casein kinase I alpha S-like; casein kinase I isoform alpha-like; CK1; CKI-alpha-like; CSNK1A1L
• Common Name: CSNK1A1L
• Gene Symbol: CSNK1A1L
• Kinase Family: CK1 Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Form: Full Length, Recombinant, Active
• Form: Liquid