Invitrogen™ Human CSNK1E (CK1 ε), His Tag Recombinant Protein

Catalog No.	Quantity
PV3988	1 mg
PR5147A	100 μg

Catalog No. PV3988 Supplier Invitrogen™ Supplier No. PV3988

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

CSNK1E (CK1 epsilon) is a serine/threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis. CSNK1E phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.

Specifications

• Accession Number: P49674
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 4mM DTT, 50% glycerol, 0.04% Triton X-100, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
• Gene ID (Entrez): 1454
• Molecular Weight (g/mol): 52.3 kDa
• Name: Human CSNK1E (CK1 ε), His Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: AI426939; AI551861; AW457082; casein kinase 1; casein kinase 1 epsilon; casein kinase 1, epsilon; casein kinase I isoform epsilon; CK1e; CK1epsilon; CKI, epsilon; CKIe; CKIepsilon; CKI-epsilon; Csnk1e; HCKIE; KC1 epsilon; KC1epsilon; MGC10398; OTTHUMP00000063258; OTTHUMP00000063263; RP1-5O6.1; tau
• Common Name: CK1 epsilon
• Gene Symbol: CSNK1E
• Kinase Family: CK1 Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.04% Triton¤ X-100, 4 mM DTT, 50% glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Kinase Group: Ser⁄Thr Kinases: CK1 Group
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Form: Full Length
• Form: Liquid
• Research Category: Drug Development