Invitrogen™ Human CSNK1E (CK1 ε), His Tag Recombinant Protein

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

CSNK1E (CK1 epsilon) is a serine/threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis. CSNK1E phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.

Specifications

• Accession Number: P49674
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM tris HCl with 0.04% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 4 mM DTT, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 1454
• Molecular Weight (g/mol): 52.3 kDa
• Name: Human CSNK1E (CK1 ε), His Tag
• Quantity: 10 μg
• Regulatory Status: For research use only. Not for use in diagnostic procedures
• Gene Alias: AI426939; AI551861; AW457082; casein kinase 1; casein kinase 1 epsilon; casein kinase 1, epsilon; casein kinase I isoform epsilon; CK1e; CK1epsilon; CKI, epsilon; CKIe; CKIepsilon; CKI-epsilon; Csnk1e; HCKIE; KC1 epsilon; KC1epsilon; MGC10398; OTTHUMP00000063258; OTTHUMP00000063263; RP1-5O6.1; tau
• Common Name: CK1 epsilon
• KinaseFamily: CK1
• Product Type: CSNK1E (CK1 αμ) Recombinant Human Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Expression System: Insect cells
• Protein Family: Kinase and inhibitors
• Form: Liquid
• Protein Subtype: Serine/threonine kinase