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TARGETMOL CHEMICALS INC CSRM617 HYDROCHLORIDE 10MG
Supplier: TARGETMOL CHEMICALS INC T10896L10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2 a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]purity: 99%
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