CTLA4 Detection Set (Risk Free), ProSci

Catalog No.	Quantity
16-595-602	1 Set

Catalog No. 16-595-602 Supplier ProSci LLC Supplier No. RF16010SET

Description

Mouse Monoclonal Detection Sets

CTLA4 Monoclonal specifically detects CTLA4 in Human samples. It is validated for ELISA, Western Blot, ICC, IHC-P, Flow, IF

The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), also known as CD152, is a member of the immunoglobulin superfamily that is expressed by activated T cells and transmits an inhibitory signal to T cells (1,2). Both it and the homologous T-cell co-stimulatory protein CD28 bind to CD80 (B7-H1) and CD86 (B7-H2) on antigen-presenting cells (APCs) (3). Mutations in the CTLA-4 gene have been implicated in multiple autoimmune diseases (4). CTLA-4 also functions as an immune checkpoint protein, and anti- CTLA-4 antibodies have been successfully used in the treatment of cancer (5). ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

Specifications

• Antigen: CTLA4
• Applications: ELISA, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry, Immunofluorescence
• Concentration: Antibody 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS containing 0.02% sodium azide.
• Host Species: Mouse
• Immunogen: Mouse monoclonal CTLA-4 antibodies were raised against the extracellular domain of human CTLA-4.
• Purification Method: Antibodies are supplied as protein A purified IgG1.
• Quantity: 1 Set
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Antibodies can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Product Type: Detection Sets
• Form: Liquid
• Isotype: IgG1