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Medchemexpress LLC CU-CPT 4a (TLR3-IN-1) | 1279713-77-7 | 99.5% | 377.82 | 50 MG
Supplier: Medchemexpress LLC HY10847310MM/1ML
CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. It represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β.
- Potent, highly selective TLR3 signaling inhibitor.
- Represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β.
- Shows dose-dependent inhibitory effects blocking Poly (I:C)-induced TLR3 activation with an IC50 of 3.44 μM in RAW 264.7 cells.
- Competes with dsRNA for binding to TLR3 with a Ki of 2.96 μM.
- For research use only.
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