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AdipoGen Cucurbitacin B (1 mg)

Supplier: AdipoGen AGCN20472M001

Chemical. CAS: 6199-67-3. Formula: C32H46O8. MW: 558.7. Isolated from Cucumis melo L. Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation. Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties. Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell lines. Shown to inhibit STAT 3 phosphorylation and expression levels and blocks JAK2 activity, as well as the transcriptional activity of HIF1alpha and NF-kappaB. Antioxidant. Serves as an ecdysteroid receptor antagonist in Drosophila.
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