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Medchemexpress LLC Cucurbitacin E | 18444-66-1 | 556.69 | 1 MG
Supplier: Medchemexpress LLC HYN04171MG
Cucurbitacin E is a natural compound sourced from Cucurbitaceae plants. It significantly suppresses the activity of the cyclin B1/CDC2 complex and is intended for research use only. This compound exhibits growth inhibition in various cancer cell lines and reduces obesity in mice by targeting the JAK-STAT5 signaling pathway.
- Natural compound from Cucurbitaceae plants.
- Significantly suppresses the activity of the cyclin B1/CDC2 complex.
- Exhibits growth inhibition in various cancer cell lines including human prostate, CNS, breast, colon, HL-60, HSC-T6, HT-1080, HeLa, HepG2, JY, MCF7, and U-937 cells.
- Induces morphological changes in primary colon cancer cells and inhibits tumor growth by arresting the cell cycle in the G2/M phase.
- Reduces obesity and related metabolic dysfunction in mice.
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