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Cayman Chemical Curcumin, 458-37-7, 5 g

Supplier: Cayman Chemical 810255

Molecular Formula C21H20O6, Purity ≥90%, Formula Weight 368.4, Synonyms: 1,7-bis(4-hydroxy-3-methoxyphenyl)-1E,6E-heptadiene-3,5-dione, Indian Saffron, Turmeric yellow; A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 M) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-, IL-1, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 mol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats.
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