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Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 5 MG
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Supplier:  Medchemexpress LLC HY153274A5MG

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CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects.

  • IGF2BP2 inhibitor.
  • Inhibits IGF2BP2 interaction with m6A-modified target transcripts.
  • Induces apoptosis and differentiation.
  • Demonstrates anti-leukemic effects.
  • Effective in reducing Gln uptake and impairing mitochondrial function in AML cells.
  • Inhibits colony-forming ability of leukemic mouse blasts.
  • Impairs self-renewal of LSC/LIC.
  • Delays leukemia onset and prolongs survival in vivo.

Catalog No. 50-003-72545


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