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Eurofins Discoverx Ready-to-Assay CXCR2 Chemokine Receptor Frozen Cells, 2 Vials of Cells. (HTS002RTA)

Supplier:  Eurofins Discoverx HTS002RTA

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The Ready-to-Assay CXCR2 Chemokine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. CXCL8/IL8) based activation of CXCR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CXCR2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.

Catalog No. 50-200-5325


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