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Medchemexpress LLC CXCR7 modulator 2 | 2227426-37-9 | 98.7% | 522.68 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11215450MG

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CXCR7 modulator 2 is a C-X-C Chemokine Receptor Type 7 (CXCR7) modulator with a Ki of 13 nM. It is intended for research use only.

  • Potent CXCR7-binding affinity (Ki=13 nM)
  • Demonstrates β-arrestin activity (EC50=11 nM)
  • Improved selectivity in GPCR panel
  • Improved therapeutic index in hERG patch-clamp assay
  • Moderate to high in vitro turnover in mouse-liver microsomes and hepatocytes
  • Good aqueous solubility
  • Significantly reduced cardiac fibrosis in isoproterenol-induced cardiac injury model in mice

Catalog No. 50-004-36168


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