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Cayman Chemical CyclIc AMP AChE Tracer 100dtn
Supplier: Cayman Chemical 481000100 DTN
A PDE3 inhibitor (IC50 0.4 nM) selective for PDE3 over PDE4 (IC50 1479 nM) reduces the phytohemagglutinin-induced proliferation of isolated human monocytes inhibits LPS-induced increases of TNF-a protein levels in isolated human monocytes (IC50 520 nM) increases cAMP levels in isolated human neutrophils at 10 UM inhibits electric field stimulation-induced contractile responses in isolated guinea pig trachea in a concentration-dependent manner intranasal administration inhibits histamine-induced bronchoconstriction and tracheal edema in guinea pigs at 25 w/w
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