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Medchemexpress LLC Cyclic GMP | 7665-99-8 | 99.8% | 345.21 | 25 MG
Supplier: Medchemexpress LLC 25MGHY113469
Cyclic GMP (cGMP) is an important second messenger and a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Its effects are primarily through cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and phosphodiesterases (PDEs). Cyclic GMP can also inhibit platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, thereby enhancing antiviral immune responses.
- Important second messenger.
- Major intracellular mediator of extracellular signals.
- Acts primarily through cGMP-dependent protein kinases, cGMP-gated cation channels, and phosphodiesterases.
- Can inhibit platelet adhesion and aggregation.
- Conjugate cGAMP can induce IRF3 phosphorylation and nuclear translocation.
- Enhances antiviral immune responses.
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