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Medchemexpress LLC Cyclic GMP sodium | 40732-48-7 | 99.9% | 367.19 | 25 MG
Supplier: Medchemexpress LLC 25MGHY113469A
Cyclic GMP (cGMP) sodium is an important second messenger and a major intracellular mediator of extracellular signals like nitric oxide (NO) and natriuretic peptides (NPs). Its effects are mediated through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and phosphodiesterases (PDEs). It can inhibit both platelet adhesion and aggregation, and its conjugate, cGAMP, can enhance antiviral immune responses.
- Important second messenger.
- Major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs).
- Mediates effects through cGMP-dependent protein kinases, cGMP-gated cation channels, and PDEs.
- Inhibits platelet adhesion and aggregation.
- Can enhance antiviral immune responses through its conjugate.
- Activates cGMP-stimulated phosphodiesterases synergistically with Isoprenaline.
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