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Medchemexpress LLC Cyclic GMP (TBAOH) | 99.1% | 604.68 | 1 ML
Supplier: Medchemexpress LLC HY113469B10MM/1ML
Cyclic GMP (cGMP) TBAOH is an important second messenger and a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Its effects occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses.
- Important second messenger
- Major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs)
- Affects cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs
- Can inhibit both platelet adhesion and aggregation
- A conjugate can enhance antiviral immune responses
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