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Medchemexpress LLC Cyclin K degrader 1 | 3055008-98-2 | 99.9% | 466.32 | 5 MG
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Supplier:  Medchemexpress LLC HY1611685MG

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Cyclin K degrader 1 (compound 40) is an AT7519 based Cyclin K degrader with a DC50 of 21 nM. It demonstrates an affinity for cyclin K that is approximately 500-fold higher than its affinity for CDK12.

  • Degrades cyclin K in the presence of DDB-1.
  • Achieves 99 ± 1 % cyclin K degradation.
  • Has a DC50 of 21 nM.
  • Exhibits Dmax >95%.
  • Features a CDK12 Kd of 1000 nM.

Catalog No. 50-003-94552


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