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Medchemexpress LLC Cyclo(L-arginyl-L-leucyl-D-seryl-L-lysyl-L-a-aspartyl-L-lysyl) (TFA) | 99.7% | 841.88 | 10 MG
SDP

Catalog No. 5000423804
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Cyclo(RLsKDK) (TFA) is a specific inhibitor of metalloproteinase ADAM8, with an IC50 value of 182 nM. This compound holds potential for therapeutic applications in various inflammatory diseases and different types of cancer.

  • Inhibits metalloproteinase ADAM8 with an IC50 of 182 nM.
  • Shows potential for applications in inflammatory diseases and cancer.
  • Promotes ADAM8 activation and CD23 shedding.
  • Increases the activity of pro-ADAM8.
  • Causes ERK1/2 phosphorylation.
  • Reduces cell invasion.
  • Significantly reduces tumor load in in vivo models.
  • Improves the survival rate in pancreatic ductal adenocarcinoma models.
  • Reduces soluble ADAM8 content and metastasis in PDAC models.

Catalog No. 50-004-23804 Supplier Medchemexpress LLC Supplier No. HYP1676A10MG
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Cyclo(RLsKDK) (TFA) is a specific inhibitor of metalloproteinase ADAM8, with an IC50 value of 182 nM. This compound holds potential for therapeutic applications in various inflammatory diseases and different types of cancer.

  • Inhibits metalloproteinase ADAM8 with an IC50 of 182 nM.
  • Shows potential for applications in inflammatory diseases and cancer.
  • Promotes ADAM8 activation and CD23 shedding.
  • Increases the activity of pro-ADAM8.
  • Causes ERK1/2 phosphorylation.
  • Reduces cell invasion.
  • Significantly reduces tumor load in in vivo models.
  • Improves the survival rate in pancreatic ductal adenocarcinoma models.
  • Reduces soluble ADAM8 content and metastasis in PDAC models.

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