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Medchemexpress LLC Cyclo(L-arginylglycyl-L-a-aspartyl-D-phenylalanyl-N-methyl-L-valyl) | 188968-51-6 | 99.8% | 588.66 | 200 MG
SDP

Catalog No. 5000391491
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Cilengitide (HY-16141) is a blood-brain barrier-permeable integrin antagonist. It inhibits the binding of ανβ3 and ανβ5 to Vitronectin and also inhibits TGF-β/Smad signaling, mediating PD-L1 expression. Cilengitide induces apoptosis and exhibits an antiangiogenic effect in research against glioblastoma and other cancers.

  • BΒB-permeable integrin antagonist.
  • Inhibits binding to Vitronectin.
  • Inhibits TGF-β/Smad signaling.
  • Mediates PD-L1 expression.
  • Induces apoptosis.
  • Shows antiangiogenic effect.

Catalog No. 50-003-91491 Supplier Medchemexpress LLC Supplier No. HY16141200MG
May include imposed supplier surcharges.
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Cilengitide (HY-16141) is a blood-brain barrier-permeable integrin antagonist. It inhibits the binding of ανβ3 and ανβ5 to Vitronectin and also inhibits TGF-β/Smad signaling, mediating PD-L1 expression. Cilengitide induces apoptosis and exhibits an antiangiogenic effect in research against glioblastoma and other cancers.

  • BΒB-permeable integrin antagonist.
  • Inhibits binding to Vitronectin.
  • Inhibits TGF-β/Smad signaling.
  • Mediates PD-L1 expression.
  • Induces apoptosis.
  • Shows antiangiogenic effect.

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