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Medchemexpress LLC Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl) | 862772-11-0 | 98.1% | 578.64 | 25 MG

Supplier: Medchemexpress LLC 25MGHYP2300
Cyclo(Arg-Gly-Asp-D-Phe-Cys) is a cyclic RGD peptide with high affinity to αvβ3. It disrupts cell integrin interactions and is capable of inhibiting pluripotent marker expression in embryonic stem cells (ESCs), as well as reducing the tumorigenic potential of mESCs in vivo. This compound is suitable for use in tumor research.
- Has high affinity to αvβ3.
- Disrupts cell integrin interactions.
- Inhibits pluripotent marker expression in embryonic stem cells (ESCs).
- Reduces tumorigenic potential of mESCs in vivo.
- Down-regulates transcription factors Oct 4, Sox 2, and Nanog of mESCs.
- Inhibits integrin gene expression in mESC-col I constructs.
- Promotes aggregate formation and detachment from the surface in mESC.
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