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Medchemexpress LLC Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl), 2,2,2-trifluoroacetate (1:1) | 500577-51-5 | 99.6% | 717.69 | 25 MG
Supplier: Medchemexpress LLC 25MGHYP0023A
Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. This compound targets tumor microvasculature and cancer cells through specific binding to the αvβ3 integrin on the cell surface. It can be prepared with high radiochemical purity and specific activity, showing in vitro stability and moderate protein binding.
- Potent and selective inhibitor of αvβ3 integrin.
- IC50 of 0.94 nM for αvβ3 integrin.
- Targets tumor microvasculature and cancer cells.
- Exhibits high radiochemical purity (>97%).
- Shows in vitro stability.
- Suitable for MicroPET imaging to reflect αvβ3-targeted tracer accumulation.
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