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Cayman Chemical Cyclo Phe-Pro 100mg
Supplier: Cayman Chemical 34758100 MG
A P-gp inhibitor (IC50 0 63 nM) selective for P-gp over BCRP (IC50 3700 nM) as well as MRP1 MRP2 and MRP3 at 100 UM inhibits transepithelial basal-to-apical transport of paclitaxel in MDCK monolayers overexpressing P-gp (IC50 35 4 nM) inhibits tumor growth and induces tumor regression in an HT-29 mouse xenograft model at 10 and 20 mg/kg respectively in combination with paclitaxel
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