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Cayman Chemical Cyclo RGDyKtrIfluoroACTAt 10mg
SDP

Supplier:  Cayman Chemical 3517310 MG

Encompass_Preferred

A PXR antagonist (IC50 0 51 UM) selective for PXR over 10 additional nuclear receptors at 5 UM as well as over a panel of 384 kinases at 10 UM inhibits rifampicin-induced PXR activation from 0 1-10 UM inhibits rifampicin-induced CYP3A4 activity in primary human hepatocytes inhibits PXR agonist-induced CYP3A4-mediated metabolism of midazolam and paclitaxel in hPXR-tg mice at 200 mg/kg

Catalog No. 50-291-0427


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