Apexbio Technology LLC Cyclobenzaprine HCl 6202-23-9 5g

Supplier:  Apexbio Technology LLC B59945000

Cyclobenzaprine HCl (CAS 6202-23-9) is a small molecule antagonist and inhibitor of the 5-HT2 receptor family exhibiting high affinity binding (Ki 62 nM) to 5-HT2 receptors and notably lower affinity for 5-HT1 receptors (Ki 2900 nM) 5-HT2 receptors comprising the 5-HT2A 5-HT2B and 5-HT2C subtypes are G protein-coupled receptors with significant roles in central nervous system signaling Cyclobenzaprine HCl has been shown to suppress both monosynaptic and polysynaptic reflex amplitudes in animal models and reduce neural firing rates suggesting inhibition of spinal reflex transmission through 5-HT2 receptor pathways This compound is utilized in neuroscience research to study serotonergic modulation of synaptic transmission and spinal reflexes

Catalog No. 50-000-87793