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Medchemexpress LLC Cycloguanil-d6 (chlorguanide triazine-d6) | 516-21-2 | 98.0% | 1 MG
Supplier: Medchemexpress LLC HY12784S1MG
Cycloguanil-d6 is a deuterium-labeled version of Cycloguanil, a dihydrofolate reductase (DHFR) inhibitor. It disrupts the folate metabolic pathway, affecting nucleotide synthesis and DNA replication. This compound inhibits DHFR in Plasmodium, useful in malaria research, and also in human cancer cells, demonstrating anticancer properties. Stable heavy isotopes are incorporated for use as tracers in drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits dihydrofolate reductase (DHFR).
- Disrupts the folate metabolic pathway.
- Affects nucleotide synthesis and DNA replication.
- Useful in malaria research.
- Demonstrates anticancer properties.
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