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Medchemexpress LLC Cycloguanil hydrochloride | 152-53-4 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HY12784A10MM/1ML
Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. It blocks the folate metabolic pathway, affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil inhibits DHFR in *Plasmodium*, making it useful in malaria research. It also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, demonstrating anticancer activity.
- Inhibits dihydrofolate reductase (DHFR)
- Blocks folate metabolic pathway
- Interferes with DNA replication
- Useful in malaria research
- Exhibits anticancer activity
- Potently inhibits transcriptional activity of STAT3
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