Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000341933

Medchemexpress LLC Cycloguanil hydrochloride | 152-53-4 | 99.9% | 25 MG
SDP

Catalog No. 5000341933
Encompass_Preferred

Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. It functions by blocking the folate metabolic pathway, which affects nucleotide synthesis and interferes with DNA replication. It inhibits DHFR in Plasmodium, making it relevant for malaria research. Additionally, it exhibits anticancer activity by potently inhibiting DHFR in human cancer cells and blocking the transcriptional activity of STAT3.

  • Inhibits dihydrofolate reductase (DHFR)
  • Blocks the folate metabolic pathway
  • Interferes with DNA replication and nucleotide synthesis
  • Relevant for malaria research through Plasmodium DHFR inhibition
  • Exhibits anticancer activity in human cancer cells
  • Blocks transcriptional activity of STAT3

Catalog No. 50-003-41933 Supplier Medchemexpress LLC Supplier No. 25MGHY12784A
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. It functions by blocking the folate metabolic pathway, which affects nucleotide synthesis and interferes with DNA replication. It inhibits DHFR in Plasmodium, making it relevant for malaria research. Additionally, it exhibits anticancer activity by potently inhibiting DHFR in human cancer cells and blocking the transcriptional activity of STAT3.

  • Inhibits dihydrofolate reductase (DHFR)
  • Blocks the folate metabolic pathway
  • Interferes with DNA replication and nucleotide synthesis
  • Relevant for malaria research through Plasmodium DHFR inhibition
  • Exhibits anticancer activity in human cancer cells
  • Blocks transcriptional activity of STAT3

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.