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Medchemexpress LLC Cyclopamine | 4449-51-8 | 411.62 | 200 MG

Supplier: Medchemexpress LLC HY17024200MG
Cyclopamine is a steroidal alkaloid and a selective Smo inhibitor that acts as a Hedgehog (Hh) pathway antagonist, with an IC50 of 46 nM in Hh cell assays. It is used in research for its ability to suppress cell growth and inhibit Hh signaling.
- Hedgehog (Hh) pathway antagonist
- Selective Smo inhibitor
- Suppresses cell growth
- Inhibits Hh signaling through direct interaction with Smo
- Suitable for research and analytical applications
- Induces tumor remission in medulloblastoma models
- Blocks tumor formation in pancreatic adenocarcinoma cells
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