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Medchemexpress LLC Cyclophosphamide hydrate | 6055-19-2 | 99.9% | 500 MG
Supplier: Medchemexpress LLC HY17420A500MG
Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. It induces outer membrane blebbing, leads to DNA fragmentation, and induces cleavage of caspase 3 and caspase 7 substrate PARP in 9L/P450 cells. In C3H mice bearing SW1 tumors, it increased the percentage of cells that stained for CD3, CD4, or CD8 in both spleens and tumors.
- Acts as a synthetic alkylating agent
- Exhibits antineoplastic and immunosuppressive activities
- Induces DNA fragmentation and caspase cleavage
- Increases immune cell markers in spleens and tumors
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