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Medchemexpress LLC Cyclopropanecarbonitrile, 2-(7-chloro-2-(5-chloro-3-(trifluoromethyl)-pyrazol-1-yl)methyl-) | 2026635-66-3 | 99.1% | 428.20 g/mol | C17H10Cl2F3N5O | 5 MG
SDP

Catalog No. 5000241344
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GNE 5729 is a brain-permeable positive allosteric modulator of the NMDA receptor (NMDAR) with preferential potency at GluN2A subunits. It is used in biochemical, cellular, and in vivo pharmacology studies to probe NMDAR modulation and subtype selectivity.

  • Brain-permeable compound suitable for central nervous system studies.
  • High potency at GluN2A with EC50 = 37 nM.
  • Lower potency at GluN2C and GluN2D (EC50 = 4.7 μM and 9.5 μM) indicating subtype selectivity.
  • High purity (99.1% by LCMS) suitable for pharmacology assays.
  • Solid form, white to yellow, stable for handling and storage.

Catalog No. 50-002-41344 Supplier Medchemexpress LLC Supplier No. HY1074095MG
May include imposed supplier surcharges.
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GNE 5729 is a brain-permeable positive allosteric modulator of the NMDA receptor (NMDAR) with preferential potency at GluN2A subunits. It is used in biochemical, cellular, and in vivo pharmacology studies to probe NMDAR modulation and subtype selectivity.

  • Brain-permeable compound suitable for central nervous system studies.
  • High potency at GluN2A with EC50 = 37 nM.
  • Lower potency at GluN2C and GluN2D (EC50 = 4.7 μM and 9.5 μM) indicating subtype selectivity.
  • High purity (99.1% by LCMS) suitable for pharmacology assays.
  • Solid form, white to yellow, stable for handling and storage.

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