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Selleck Chemical LLC Cyclosporin A S2286-1g

Supplier: Selleck Chemical LLC S22861G

Cyclosporin A a non-polar cyclic oligopeptide is an immunosuppressive agent that binds to cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay Cyclosporin A is generally given following transplant surgery to prevent rejection and has been used to test its toxic effect on a perfused 3D proximal tubule model Cyclosporin A (NSC 290193) can be used to induce animal models of Chronic Rejection of Liver Transplantation
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