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Cayman Chemical CYP2C9 ReporTR RevRse Trns 1ea

Supplier: Cayman Chemical 6011211 EA

A DYRK1A inhibitor (IC50 0.4 nM) selective for DYRK1A over DYRK2 Clk1 Clk2 Clk3 Cdk2 and GSK3B (IC50s 19 7.1 9.4 54 100 and 94 nM respectively) but does inhibit DYRK1B (IC50 2.7 nM) inhibits DYRK1A-induced increases in tau phosphorylation in a cell-based assay (IC50 590 nM)
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