Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ABclonal Technology CYP2D6 Rabbit pAb
Supplier: ABclonal Technology A1299100UL
This gene encodes a cytochrome P450 enzyme, part of the monooxygenase family involved in drug metabolism and the synthesis of cholesterol, steroids, and lipids. It is located in the endoplasmic reticulum and metabolizes about 25% of commonly prescribed drugs, including antidepressants, antipsychotics, analgesics, and antiemetics. The gene is highly polymorphic, with certain alleles leading to the poor metabolizer phenotype, characterized by reduced drug metabolism. Some individuals may lack functional protein due to two null alleles, while others may have no gene copies. Individuals with the ultrarapid metabolizer phenotype may have 3 or more active gene copies. Alternative splicing of this gene results in various isoforms.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?