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Apexbio Technology LLC Cyproheptadine hydrochloride 969-33-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B33095.1
Cyproheptadine hydrochloride (969-33-5) is a small-molecule antagonist targeting serotonin (5-HT) and histamine receptors especially the 5-HT2A subtype It is designed to competitively antagonize these receptors thereby regulating serotonergic and histaminergic signaling pathways Cyproheptadine hydrochloride exerts its biological activity primarily through serotonin and histamine receptor antagonism and also exhibits antimuscarinic effects In in vitro studies cyproheptadine hydrochloride demonstrates inhibition of serotonin-enhanced platelet aggregation induced by ADP with an IC50 value commonly reported near 20 nM toward human 5-HT2A receptors Based on these pharmacological properties cyproheptadine hydrochloride holds research potential in antithrombotic studies post-gastrectomy dumping syndrome migraine pruritic dermatoses anorexia and pituitary-dependent Cushing s syndrome
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