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Cayman Chemical CytIdIn 3-monphosphate 50mg

Supplier: Cayman Chemical 3383350 MG

A P2X7 receptor antagonist inhibits BzATP-evoked intracellular calcium influx in 1321N1 cells expressing human rat and mouse receptors (IC50s 20 42 and 150 nM respectively) inhibits BzATP-induced YO-PRO dye uptake and IL-1B release from THP-1 cells (IC50s 6.6 and 37 nM respectively) reduces thermal hyperalgesia in rats at 30 100 and 300 Umol/kg i.p. reduces thermal and mechanical hyperalgesia in a rat MRMT-1 mammary carcinoma model of cancer-induced bone pain at 40 mg/kg
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