Cytochalasin B, MP Biomedicals™

Description

Disrupts contractile microfilaments by inhibiting actin polymerization. Cytochalasin B, MP Biomedicals is a cell permeable fungal toxin that is an important tool for cytological research. It induces DNA fragmentation, inhibits cell division, disrupts many

Cytochalasin B is one of a group of fungal metabolites that interfere with a wide variety of cellular movements. It is a useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. It is used as a probe for the two hexose-transport systems in rat L6 myoblasts.

Specifications

Chemical Identifiers

• CAS: 14930-96-2
• Molecular Formula: C29H37NO5
• Molecular Weight (g/mol): 479.62
• MDL Number: MFCD00077704
• InChI Key: GBOGMAARMMDZGR-UHFFFAOYNA-N
• Synonym: cytochalasin b, cytochalasin b from helminthosporium dematioideum
• PubChem CID: 44634701
• IUPAC Name: 16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,12aH,13H,14H,15H,15aH,16H,17H,18H-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
• SMILES: CC1C2C(CC3=CC=CC=C3)NC(=O)C22OC(=O)C=CC(O)CCCC(C)CC=CC2C(O)C1=C

• Melting Point: 216°C to 226°C
• Quantity: 25 mg
• Solubility Information: Soluble in methanol (20mg/mL, clear, colorless solution) or ethanol, DMSO (10mg/mL), DMF; Insoluble in water.
• Formula Weight: 479.6g/mol
• Physical Form: Powder

Safety and Handling

Recommended Storage

Store at −20°C, desiccate, protect from light.

WARNING: Reproductive Harm - www.P65Warnings.ca.gov