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Apexbio Technology LLC Cytochalasin D 22144-77-0 10mg
SDP

Supplier:  Apexbio Technology LLC B664510

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Cytochalasin D is a selective inhibitor of actin polymerization with a reported IC50 value of approximately 25 nM It exerts its biological effect by disrupting the formation and stability of actin filaments thereby influencing cellular processes dependent on cytoskeletal organization Through this mechanistic action Cytochalasin D induces cell cycle arrest at the G1-S transition via activation of p53-related signaling pathways In neuronal studies treatment with Cytochalasin D interferes with filopodial and lamellipodial dynamics by limiting protrusion elongation Additionally in vitro investigations demonstrated its utility in the study of virus-host interactions where blockade of actin polymerization inhibits pathogen entry and replication making Cytochalasin D a relevant reagent in cellular biology and virology research

Catalog No. 50-000-63864


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