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Cytochalasin D, MP Biomedicals™

Catalog No. MP215077110 Shop All MP Biomedicals, Inc Products
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MP215077110 10 mg
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Catalog No. MP215077110 Supplier MP Biomedicals, Inc Supplier No. 0215077110
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Description

Disrupts actin filaments and inhibits actin polymerization. Cytochalasin D, MP Biomedicals is a cell-permeable fungal toxin that binds to the barbed end of actin filaments, inhibiting both the association and dissociation of subunits. It possesses antibio

This compound disrupts actin microfilaments and activates the p53-dependent pathways, causing arrest of the cell cycle at the G1-S transition.

  • Inhibits smooth muscle contraction
  • Inhibits insulin-stimulated, but not basal, transport of glucose
  • Possesses antibiotic and antitumor activity
  • Impairs maintenance of long term potentiation (LTP) of actin filaments
  • Implicated in promoting conditions favorable for depolymerizing actin
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 22144-77-0
Molecular Formula C30H37NO6
Molecular Weight (g/mol) 507.627
InChI Key SDZRWUKZFQQKKV-DKLHZCHASA-N
Synonym cytochalasin d
PubChem CID 131668624
SMILES CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O

Specifications

Melting Point 193°C to 195°C (literature)
Quantity 10 mg
Solubility Information Soluble in chloroform (10g/mL, clear, colorless solution), CH2Cl2 (10mg/ mL, clear colorless solution), DMSO and ethanol.
Formula Weight 507.6
Physical Form Powder

Safety and Handling

Recommended Storage Store at −20°C, protect from light, dessicated.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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