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Cayman Chemical CytochalasIn H 1mg

Supplier: Cayman Chemical 184341 MG

A pan-CDK inhibitor (IC50s 3 1 1 and 4 nM for CDK1 CDK2 CDK5 and CDK9 respectively) that inhibits DNA synthesis in A2780 ovarian cancer cells (IC50 4 nM) 5 mg/kg prevents tumor growth by 50 in an A2780 ovarian carcinoma mouse xenograft model active against a broad spectrum of human tumor cell lines in vitro (IC50s 7-17 nM)
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