Sigma Aldrich Fine Chemicals Biosciences CytoSoftR Imaging 96-Well

Supplier:  Sigma Aldrich Fine Chemicals Biosciences CC315

The rigidity of the cells substrate (such as the extracellular matrix) can have profound effect on cell function including morphology differentiation and gene expression. Youngs elastic modulus is a mechanical property that measures the stiffness of a solid material. It defines the relationship between stress and strain in a material and is measured in kPa.CytoSoft(R) plates provide a tool to culture cells on substrates with defined rigidities covering a broad physiological range (0.2 kPa- 64 kPa). On the bottom of each well there is a thin layer of specially formulated biocompatible silicone whose elastic modulus (rigidity) is carefully measured and certified. The surfaces of the gels are functionalized to form covalent bonds with amines on proteins. The gel readily binds to purified ECM proteins such as PureCol type I collagen (5006) prior to cell addition. CytoSoft(R) Imaging plates are designed for high-reSOLUTIONon imaging where low autofluorescence andexceptional optical cl

Catalog No. 50-290-5566