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Medchemexpress LLC CZC-8004 | 916603-07-1 | 99.81% | 309.34 | 50 MG
Supplier: Medchemexpress LLC HY11113810MM/1ML
CZC-8004 is a pan-kinase inhibitor that shows potential for cancer research. It exhibits IC50 values of 650 nM for EGFR WT and 437 nM for VEGFR2 V916M. In vitro, CZC-8004 (1 μM) demonstrates specific targeting capabilities towards H1975 cells that possess the VEGFR2 V916M mutation, with observed activity across a panel of human cancer cell lines.
- Exhibits IC50 values of 650 nM for EGFR WT and 437 nM for VEGFR2 V916M.
- Can be used in the study of cancer.
- Shows certain targeting ability to H1975 cells with VEGFR2 V916M mutation.
- Observed activity across human cancer cell lines CRL2064 (wild type), PC9G (EGFR T790M), H3122CR1 (ALK L1196M), and H1975 (VEGFR2 V916M).
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