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Medchemexpress LLC D-Arabinopyranose-13C5 | 28697-53-2 | 1 MG
SDP

Catalog No. 5000419895
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D-Arabinopyranose-13C5 is a 13C labeled version of D-Arabinopyranose. Its ring-opened form, D-arabinose, is an orally active antidepressant and an inhibitor of *C. elegans* growth, with an IC50 of 7.5 mM. D-arabinose can cross the blood-brain barrier and selectively interfere with the metabolism of D-ribose and D-fructose, thereby inhibiting nematode growth. It also inhibits cell biofilm synthesis, demonstrating antibacterial activity. D-arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, leading to CRTC1 transcription and antidepressant-like effects.

  • Can be used as a tracer.
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Catalog No. 50-004-19895 Supplier Medchemexpress LLC Supplier No. HYN7082S1MG
May include imposed supplier surcharges.
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D-Arabinopyranose-13C5 is a 13C labeled version of D-Arabinopyranose. Its ring-opened form, D-arabinose, is an orally active antidepressant and an inhibitor of *C. elegans* growth, with an IC50 of 7.5 mM. D-arabinose can cross the blood-brain barrier and selectively interfere with the metabolism of D-ribose and D-fructose, thereby inhibiting nematode growth. It also inhibits cell biofilm synthesis, demonstrating antibacterial activity. D-arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, leading to CRTC1 transcription and antidepressant-like effects.

  • Can be used as a tracer.
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

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