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Medchemexpress LLC D-arabinose | 10323-20-3 | 10 MM 1 ML
Supplier: Medchemexpress LLC HYN235310MM/1ML
D-Arabinose is an orally active antidepressant and a growth inhibitor of C. elegans. It penetrates the blood-brain barrier, selectively interferes with the metabolism of D-ribose and D-fructose, and inhibits nematode growth. It also inhibits cell biofilm synthesis, exhibits antibacterial activity, and activates the ACSS2-PPARγ/TFEB-CRTC1 axis to induce CRTC1 transcription and antidepressant-like effects.
- Orally active antidepressant
- Inhibits C. elegans growth
- Penetrates the blood-brain barrier
- Interferes with D-ribose and D-fructose metabolism
- Inhibits nematode growth
- Inhibits cell biofilm synthesis
- Exerts antibacterial activity
- Activates ACSS2-PPARγ/TFEB-CRTC1 axis
- Induces CRTC1 transcription
- Improves depressive-like behavior in mouse models
- Reverses CRTC1 and BDNF downregulation
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